2009 JAN 5 -- "Uterine leiomyosarcoma during pregnancy is an extremely rare event. The incidence of meningioma during pregnancy is comparable with that in nonpregnant women of the same age group," investigators in Vienna, Austria report.
"We report a case of both - a primary uterine leiomyosarcoma and additionally all atypical meningioma of the brain both diagnosed during pregnancy. The patient was admitted with generalised seizures at 31 weeks of gestation. A tumoural mass was detected and initial conservative treatment was started. The patient delivered her infant via caesarean section, at 34 weeks of gestation. During caesarean section a pedunculated uterine fibroid was removed and total gross resection due to the brain tumour was also performed. Histopathological diagnosis of both tumours revealed an atypical meningioma of the brain and a uterine leiomyosarcoma. The patient underwent laparatomy and received six cycles of adjuvant chemotherapy. We are the first to report a case of a woman with two separate primary neoplasms both diagnosed during pregnancy," wrote B. Bodneradler and colleagues, University of Vienna, Medical Department.
The researchers concluded: "Treatment options seem to be reduced in pregnant women and mainly depend on the patient's condition as well as the gestational age at presentation."
Bodneradler and colleagues published their study in Anticancer Research (Primary Uterine Leiomyosarcoma and Primary Atypical Meningioma Diagnosed during Pregnancy. Anticancer Research, 2008;28(5B):3083-3085).
For additional information, contact B. Bodneradler, University of Vienna, School Medical, Dept. of Obstetrics & Gynecology, Wahringer Gurtel 18-20, A-1090 Vienna, Austria.
The publisher of the journal Anticancer Research can be contacted at: International Institute Anticancer Research, Editorial Office 1ST km Kapandritiou-Kalamou Rd. Kapandriti, PO Box 22, Athens 19014, Greece.
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